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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5017
Target Type SINGLE PROTEIN
Preferred Name Serotonin 4 (5-HT4) receptor
Synonyms 5-HT-4 | 5-HT4 | 5-hydroxytryptamine receptor 4 | HTR4 | Serotonin receptor 4
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > serotonin receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 4 SINGLE PROTEIN O70528

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005768 (endosome)
GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004993 (G-protein coupled serotonin receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007210 (serotonin receptor signaling pathway)
GO:0007268 (chemical synaptic transmission)
GO:0032098 (regulation of appetite)

Target Cross References - Protein

canSAR O70528
UniProt O70528

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001520 (5HT4_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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