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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4912
Target Type SINGLE PROTEIN
Preferred Name Fructose-bisphosphate aldolase class 2
Synonyms FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase class 2 | Fructose-bisphosphate aldolase class II | JW2892 | fba | fbaA | fda
Organism Escherichia coli K-12
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Fructose-bisphosphate aldolase class 2 SINGLE PROTEIN P0AB71

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005618 (cell wall)
GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0004332 (fructose-bisphosphate aldolase activity)
GO:0005515 (protein binding)
GO:0008270 (zinc ion binding)
GO:0016829 (lyase activity)
GO:0016832 (aldehyde-lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0006094 (gluconeogenesis)
GO:0006096 (glycolytic process)

Target Cross References - Protein

canSAR P0AB71
IntAct P0AB71
UniProt P0AB71 P11604 Q2M9R7

Target Cross References - Domain

InterPro IPR000771 (FBA_II.)
IPR006411 (Fruct_bisP_bact.)
IPR013785 (Aldolase_TIM.)
Pfam PF01116 (F_bP_aldolase)

Target Cross References - Structure

PDBe 1B57 1DOS 1GYN 1ZEN
CREDO 1B57 1DOS 1GYN 1ZEN
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