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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4868
Target Type SINGLE PROTEIN
Preferred Name Aminopeptidase A
Synonyms AP-A | Aminopeptidase A | CD_antigen=CD249 | EAP | ENPEP | Glutamyl aminopeptidase
Organism Sus scrofa
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m1 family

Target Components

Component Description Relationship Accession
Glutamyl aminopeptidase SINGLE PROTEIN Q95334

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0042277 (peptide binding)
GO:0046872 (metal ion binding)
GO:0070006 (metalloaminopeptidase activity)
GO Biological Process GO:0003081 (regulation of systemic arterial blood pressure by renin-angiotensin)
GO:0006508 (proteolysis)
GO:0008217 (regulation of blood pressure)
GO:0008283 (cell proliferation)
GO:0016477 (cell migration)
GO:0043171 (peptide catabolic process)

Target Cross References - Protein

canSAR Q95334
UniProt Q95334

Target Cross References - Domain

InterPro IPR001930 (Peptidase_M1.)
IPR014782 (Peptidase_M1_N.)
IPR024571 (ERAP1-like_C_dom.)
IPR033508 (Aminopeptidase_A.)
IPR034016 (M1_APN-typ.)
Pfam PF01433 (Peptidase_M1)
PF11838 (ERAP1_C)
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