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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4771
Preferred Name Potassium-transporting ATPase beta chain
Synonyms Atp4b | Gastric H(+)/K(+) ATPase subunit beta | Potassium-transporting ATPase subunit beta | Proton pump beta chain
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • transporter > primary active transporter > p-type atpase > hydrogen potassium atpase
  • enzyme > hydrolase

Target Components

Component Description Relationship Accession
Potassium-transporting ATPase subunit beta SINGLE PROTEIN P18598

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095199 Potassium-transporting ATPase PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005575 (cellular_component)
GO:0005886 (plasma membrane)
GO:0005890 (sodium:potassium-exchanging ATPase complex)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0008900 (hydrogen:potassium-exchanging ATPase activity)
GO Biological Process GO:0001696 (gastric acid secretion)
GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006813 (potassium ion transport)
GO:0006814 (sodium ion transport)
GO:0007155 (cell adhesion)
GO:0010243 (response to organonitrogen compound)
GO:0015992 (proton transport)
GO:0032496 (response to lipopolysaccharide)
GO:1902600 (hydrogen ion transmembrane transport)

Target Cross References - Protein

canSAR P18598
Reactome R-RNO-936837 (Ion transport by P-type ATPases.)
UniProt P18598

Target Cross References - Domain

InterPro IPR000402 (Na/K_ATPase_sub_beta.)
Pfam PF00287 (Na_K-ATPase)