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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4768
Target Type SINGLE PROTEIN
Preferred Name Acetylcholinesterase
Synonyms ACHE | AChE | Acetylcholinesterase
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Acetylcholinesterase SINGLE PROTEIN P23795

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005615 (extracellular space)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0030054 (cell junction)
GO:0031225 (anchored component of membrane)
GO:0031594 (neuromuscular junction)
GO:0045202 (synapse)
GO Molecular Function GO:0001540 (beta-amyloid binding)
GO:0003990 (acetylcholinesterase activity)
GO:0004104 (cholinesterase activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0052689 (carboxylic ester hydrolase activity)
GO Biological Process GO:0006581 (acetylcholine catabolic process)
GO:0042135 (neurotransmitter catabolic process)

Target Cross References - Protein

canSAR P23795
UniProt O97579 P23795 Q08D79

Target Cross References - Domain

InterPro IPR000997 (Cholinesterase.)
IPR002018 (CarbesteraseB.)
IPR014788 (AChE_tetra.)
IPR019819 (Carboxylesterase_B_CS.)
IPR019826 (Carboxylesterase_B_AS.)
IPR029058 (AB_hydrolase.)
Pfam PF00135 (COesterase)
PF08674 (AChE_tetra)
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