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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4725
Target Type SINGLE PROTEIN
Preferred Name Aryl hydrocarbon receptor
Synonyms AHR | Ah receptor | AhR | Aryl hydrocarbon receptor
Organism Oryctolagus cuniculus
Species Group No
Protein Target Classification
  • transcription factor

Target Components

Component Description Relationship Accession
Aryl hydrocarbon receptor SINGLE PROTEIN O02747

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0034751 (aryl hydrocarbon receptor complex)
GO Molecular Function GO:0003677 (DNA binding)
GO:0003700 (transcription factor activity, sequence-specific DNA binding)
GO:0004874 (aryl hydrocarbon receptor activity)
GO:0046983 (protein dimerization activity)
GO:0070888 (E-box binding)
GO Biological Process GO:0006351 (transcription, DNA-templated)
GO:0006355 (regulation of transcription, DNA-templated)
GO:0009410 (response to xenobiotic stimulus)
GO:0030522 (intracellular receptor signaling pathway)
GO:0032922 (circadian regulation of gene expression)
GO:0045892 (negative regulation of transcription, DNA-templated)
GO:0045893 (positive regulation of transcription, DNA-templated)
GO:0048511 (rhythmic process)

Target Cross References - Protein

canSAR O02747
UniProt O02747

Target Cross References - Domain

InterPro IPR000014 (PAS.)
IPR001610 (PAC.)
IPR011598 (bHLH_dom.)
IPR013655 (PAS_fold_3.)
IPR013767 (PAS_fold.)
IPR033348 (AHR.)
Pfam PF00010 (HLH)
PF00989 (PAS)
PF08447 (PAS_3)
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