ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL4655
Target Type SINGLE PROTEIN
Preferred Name Serotonin 5a (5-HT5a) receptor
Synonyms 5-HT-5A | 5-HT5A | 5-hydroxytryptamine receptor 5A | 5ht5a | Htr5a | REC17 | Serotonin receptor 5A
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > serotonin receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 5A SINGLE PROTEIN P35364

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2094123 Serotonin (5-HT) receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005791 (rough endoplasmic reticulum)
GO:0005794 (Golgi apparatus)
GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030425 (dendrite)
GO:0043204 (perikaryon)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004993 (G-protein coupled serotonin receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007187 (G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)
GO:0007210 (serotonin receptor signaling pathway)
GO:0007420 (brain development)
GO:0019933 (cAMP-mediated signaling)
GO:0021766 (hippocampus development)
GO:0032355 (response to estradiol)

Target Cross References - Protein

canSAR P35364
Guide to Pharmacology 10
Reactome R-RNO-390666 (Serotonin receptors.)
R-RNO-418594 (G alpha (i) signalling events.)
UniProt P35364

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001397 (5HT5A_rcpt.)
IPR002231 (5HT_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
spacer
spacer