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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4646
Target Type SINGLE PROTEIN
Preferred Name Serotonin 1f (5-HT1f) receptor
Synonyms 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5ht1f | Htr1f | Serotonin receptor 1F
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > serotonin receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 1F SINGLE PROTEIN P30940

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095159 Serotonin 1 (5-HT1) receptor PROTEIN FAMILY
CHEMBL2094123 Serotonin (5-HT) receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004993 (G-protein coupled serotonin receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007193 (adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway)
GO:0007210 (serotonin receptor signaling pathway)

Target Cross References - Protein

canSAR P30940
Guide to Pharmacology 5
UniProt P30940

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000450 (5HT1F_rcpt.)
IPR002231 (5HT_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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