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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4624
Target Type SINGLE PROTEIN
Preferred Name Fibonectin-binding protein C
Synonyms 85C | Acyl-CoA:diacylglycerol acyltransferase | Ag85C | Antigen 85 complex C | DGAT | Diacylglycerol acyltransferase/mycolyltransferase Ag85C | Fbps C | Fibronectin-binding protein C | fbpC | mpt45
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • surface antigen

Target Components

Component Description Relationship Accession
Diacylglycerol acyltransferase/mycolyltransferase Ag85C SINGLE PROTEIN P9WQN9

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005618 (cell wall)
GO Molecular Function GO:0004144 (diacylglycerol O-acyltransferase activity)
GO:0016740 (transferase activity)
GO:0016746 (transferase activity, transferring acyl groups)
GO:0016747 (transferase activity, transferring acyl groups other than amino-acyl groups)
GO:0050348 (trehalose O-mycolyltransferase activity)
GO Biological Process GO:0006869 (lipid transport)
GO:0009247 (glycolipid biosynthetic process)
GO:0046677 (response to antibiotic)
GO:0071769 (mycolate cell wall layer assembly)

Target Cross References - Protein

canSAR P0A4V4
UniProt L0T2K1 P0A4V4 P31953 P96806 P9WQN9

Target Cross References - Domain

InterPro IPR000801 (Esterase_put.)
IPR029058 (AB_hydrolase.)
Pfam PF00756 (Esterase)

Target Cross References - Structure

PDBe 1DQY 1DQZ 1VA5 3HRH 4MQL 4MQM 4QDO 4QDT 4QDU 4QDX 4QDZ 4QE3 4QEK
CREDO 1DQY 1DQZ 1VA5 3HRH 4MQL 4MQM 4QDO 4QDT 4QDU 4QDX 4QDZ 4QE3 4QEK
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