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Target Report Card

Target Name and Classification

Target ID CHEMBL4605
Preferred Name Oligopeptide transporter small intestine isoform
Synonyms Intestinal H(+)/peptide cotransporter | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | SLC15A1 | Solute carrier family 15 member 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc15 family of peptide transporters

Target Components

Component Description Relationship Accession
Solute carrier family 15 member 1 SINGLE PROTEIN P46059

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000088386
Ensembl ENSG00000088386
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0005903 (brush border)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0005215 (transporter activity)
GO:0005427 (proton-dependent oligopeptide secondary active transmembrane transporter activity)
GO:0015198 (oligopeptide transporter activity)
GO:0015293 (symporter activity)
GO:0015333 (peptide:proton symporter activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006857 (oligopeptide transport)
GO:0007586 (digestion)
GO:0015031 (protein transport)
GO:0015833 (peptide transport)
GO:0015992 (proton transport)
GO:0035672 (oligopeptide transmembrane transport)
Wikipedia Peptide_transporter_1

Target Cross References - Protein

canSAR P46059
Human Protein Atlas ENSG00000088386
Guide to Pharmacology 984
Open Targets ENSG00000088386
PharmGKB PA323
Reactome R-HSA-427975 (Proton/oligopeptide cotransporters.)
UniProt P46059 Q5VW82

Target Cross References - Domain

InterPro IPR000109 (POT_fam.)
IPR004768 (Oligopep_transport.)
IPR018456 (PTR2_symporter_CS.)
IPR020846 (MFS_dom.)
IPR031124 (Pept-3.)
Pfam PF00854 (PTR2)