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Target Report Card

Target Name and Classification

Target ID CHEMBL4604
Preferred Name Equilibrative nucleoside transporter 1
Synonyms Ent1 | Equilibrative NBMPR-sensitive nucleoside transporter | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter | Equilibrative nucleoside transporter 1 | Nucleoside transporter, es-type | Slc29a1 | Solute carrier family 29 member 1
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc28 and slc29 families of nucleoside transporters > slc29 facilitative nucleoside transporter family

Target Components

Component Description Relationship Accession
Equilibrative nucleoside transporter 1 SINGLE PROTEIN O54698

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0016323 (basolateral plasma membrane)
GO:0016324 (apical plasma membrane)
GO:0098794 (postsynapse)
GO Molecular Function GO:0005337 (nucleoside transmembrane transporter activity)
GO Biological Process GO:0007595 (lactation)
GO:0015858 (nucleoside transport)
GO:0015862 (uridine transport)
GO:0030431 (sleep)
GO:0060079 (excitatory postsynaptic potential)
GO:0071333 (cellular response to glucose stimulus)
GO:0071456 (cellular response to hypoxia)
GO:1901642 (nucleoside transmembrane transport)

Target Cross References - Protein

canSAR O54698
Reactome R-RNO-83936 (Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane.)
UniProt O54698

Target Cross References - Domain

InterPro IPR002259 (Eqnu_transpt.)
IPR030195 (ENT1.)
IPR034764 (ENT1/ENT2.)
IPR036259 (MFS_trans_sf.)
Pfam PF01733 (Nucleoside_tran)