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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4586
Target Type SINGLE PROTEIN
Preferred Name Seed lipoxygenase-1
Synonyms L-1 | LOX1 | LOX1.1 | Lipoxygenase-1 | Seed linoleate 13S-lipoxygenase-1
Organism Glycine max
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Seed linoleate 13S-lipoxygenase-1 SINGLE PROTEIN P08170

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0016165 (linoleate 13S-lipoxygenase activity)
GO:0016491 (oxidoreductase activity)
GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
GO:0046872 (metal ion binding)
GO:0051213 (dioxygenase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006631 (fatty acid metabolic process)
GO:0006633 (fatty acid biosynthetic process)
GO:0031408 (oxylipin biosynthetic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P08170
UniProt P08170

Target Cross References - Domain

InterPro IPR000907 (LipOase.)
IPR001024 (PLAT/LH2_dom.)
IPR001246 (LipOase_plant.)
IPR013819 (LipOase_C.)
IPR020833 (LipOase_Fe_BS.)
IPR020834 (LipOase_CS.)
IPR027433 (Lipoxygenase_dom_3.)
IPR036226 (LipOase_C_sf.)
IPR036392 (PLAT/LH2_dom_sf.)
Pfam PF00305 (Lipoxygenase)
PF01477 (PLAT)

Target Cross References - Structure

PDBe 1F8N 1FGM 1FGO 1FGQ 1FGR 1FGT 1Y4K 1YGE 2SBL 3BNB 3BNC 3BND 3BNE 3PZW 4WFO 4WHA 5EEO 5T5V 5TQN 5TQO 5TQP 5TR0
CREDO 1F8N 1FGM 1FGO 1FGQ 1FGR 1FGT 1Y4K 1YGE 2SBL 3BNB 3BNC 3BND 3BNE 3PZW 4WFO 4WHA 5EEO 5T5V 5TQN 5TQO 5TQP 5TR0
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