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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4538
Target Type SINGLE PROTEIN
Preferred Name Cytochrome P450 monooxygenase
Synonyms ABA 8'-hydroxylase 3 | Abscisic acid 8'-hydroxylase 3 | CYP707A3 | Cytochrome P450 707A3
Organism Arabidopsis thaliana
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Abscisic acid 8'-hydroxylase 3 SINGLE PROTEIN Q9FH76

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004497 (monooxygenase activity)
GO:0005506 (iron ion binding)
GO:0010295 ((+)-abscisic acid 8'-hydroxylase activity)
GO:0016491 (oxidoreductase activity)
GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
GO:0020037 (heme binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0007275 (multicellular organism development)
GO:0009414 (response to water deprivation)
GO:0009639 (response to red or far red light)
GO:0010268 (brassinosteroid homeostasis)
GO:0016125 (sterol metabolic process)
GO:0016132 (brassinosteroid biosynthetic process)
GO:0046345 (abscisic acid catabolic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR Q9FH76
Reactome R-ATH-211916 (Vitamins.)
R-ATH-5365859 (RA biosynthesis pathway.)
UniProt Q3E8G7 Q9FH76

Target Cross References - Domain

InterPro IPR001128 (Cyt_P450.)
IPR002401 (Cyt_P450_E_grp-I.)
IPR017972 (Cyt_P450_CS.)
Pfam PF00067 (p450)
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