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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4522
Target Type SINGLE PROTEIN
Preferred Name BMP-2-inducible protein kinase
Synonyms BIKE | BIKe | BMP-2-inducible protein kinase | BMP2K
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > other protein kinase group > other protein kinase nak family

Target Components

Component Description Relationship Accession
BMP-2-inducible protein kinase SINGLE PROTEIN Q9NSY1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000138756
Ensembl ENSG00000138756
GO Cellular Component GO:0005634 (nucleus)
GO:0005654 (nucleoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0019208 (phosphatase regulator activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0030500 (regulation of bone mineralization)
GO:0050790 (regulation of catalytic activity)
Wikipedia BMP2K

Target Cross References - Protein

canSAR Q9NSY1
Human Protein Atlas ENSG00000138756
IntAct Q9NSY1
Guide to Pharmacology 1941
Open Targets ENSG00000138756
PharmGKB PA134992822
Pharos Q9NSY1 (Tchem)
UniProt O94791 Q4W5H2 Q8IYF2 Q8N2G7 Q8NHG9 Q9NSY1 Q9NTG8

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR026105 (BMP-2-ind_kinase.)
IPR028182 (BMP2K_C.)
Pfam PF00069 (Pkinase)
PF15282 (BMP2K_C)

Target Cross References - Structure

PDBe 4W9W 4W9X 5I3O 5I3R 5IKW
CREDO 4W9W 4W9X 5I3O 5I3R 5IKW
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