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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4325
Target Type SINGLE PROTEIN
Preferred Name Aminopeptidase N
Synonyms Alpha-aminoacylpeptide hydrolase | Aminopeptidase N | JW0915 | pepN
Organism Escherichia coli K-12
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m1 family

Target Components

Component Description Relationship Accession
Aminopeptidase N SINGLE PROTEIN P04825

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0042277 (peptide binding)
GO:0042802 (identical protein binding)
GO:0046872 (metal ion binding)
GO:0070006 (metalloaminopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0043171 (peptide catabolic process)

Target Cross References - Protein

canSAR P04825
IntAct P04825
UniProt P04825

Target Cross References - Domain

InterPro IPR001930 (Peptidase_M1.)
IPR012779 (Peptidase_M1_pepN.)
IPR014782 (Peptidase_M1_N.)
IPR024601 (Peptidase_M1_pepN_C.)
Pfam PF01433 (Peptidase_M1)
PF11940 (DUF3458)

Target Cross References - Structure

PDBe 2DQ6 2DQM 2HPO 2HPT 2ZXG 3B2P 3B2X 3B34 3B37 3B3B 3KED 3PUU 3QJX 4Q4E 4Q4I 4XMT 4XMU 4XMV 4XMW 4XMX 4XMZ 4XN1 4XN2 4XN4 More...
CREDO 2DQ6 2DQM 2HPO 2HPT 2ZXG 3B2P 3B2X 3B34 3B37 3B3B 3KED 3PUU 3QJX 4Q4E 4Q4I 4XMT 4XMU 4XMV 4XMW 4XMX 4XMZ 4XN1 4XN2 4XN4 More...
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