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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4265
Target Type SINGLE PROTEIN
Preferred Name CG8425-PA [Drosophila melanogaster]
Synonyms Carboxylic ester hydrolase | Dmel_CG8425 | ECO:0000313|FlyBase:FBgn0010052} | Jhe | {ECO:0000313|EMBL:AAF58061.3
Organism Drosophila melanogaster
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Carboxylic ester hydrolase SINGLE PROTEIN A1ZA98

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005615 (extracellular space)
GO:0005739 (mitochondrion)
GO:0005887 (integral component of plasma membrane)
GO:0009986 (cell surface)
GO:0045202 (synapse)
GO Molecular Function GO:0004453 (juvenile-hormone esterase activity)
GO:0004872 (receptor activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0042043 (neurexin family protein binding)
GO:0052689 (carboxylic ester hydrolase activity)
GO Biological Process GO:0006719 (juvenile hormone catabolic process)
GO:0007158 (neuron cell-cell adhesion)
GO:0007416 (synapse assembly)
GO:0048149 (behavioral response to ethanol)
GO:0050804 (modulation of synaptic transmission)
GO:0060179 (male mating behavior)

Target Cross References - Protein

canSAR A1ZA98
UniProt A1ZA98

Target Cross References - Domain

InterPro IPR002018 (CarbesteraseB.)
IPR019819 (Carboxylesterase_B_CS.)
IPR019826 (Carboxylesterase_B_AS.)
IPR029058 (AB_hydrolase.)
Pfam PF00135 (COesterase)
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