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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4117
Target Type SINGLE PROTEIN
Preferred Name Zinc aminopeptidase
Synonyms M1 family aminopeptidase | Pfa-M1
Organism Plasmodium falciparum FcB1/Columbia
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m1 family

Target Components

Component Description Relationship Accession
M1 family aminopeptidase SINGLE PROTEIN O96935

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)

Target Cross References - Protein

canSAR O96935
UniProt O96935

Target Cross References - Domain

InterPro IPR001930 (Peptidase_M1.)
IPR012779 (Peptidase_M1_pepN.)
IPR014782 (Peptidase_M1_N.)
IPR024601 (Peptidase_M1_pepN_C.)
Pfam PF01433 (Peptidase_M1)
PF11940 (DUF3458)

Target Cross References - Structure

PDBe 3EBG 3EBH 3EBI 3Q43 3Q44 3T8V 4J3B 4K5L 4K5M 4K5N 4K5O 4K5P 4R5T 4R5V 4R5X 4X2U 4ZW3 4ZW5 4ZW6 4ZW7 4ZW8 4ZX3 4ZX4 4ZX5 More...
CREDO 3EBG 3EBH 3EBI 3Q43 3Q44 3T8V 4J3B 4K5L 4K5M 4K5N 4K5O 4K5P 4R5T 4R5V 4R5X 4X2U 4ZW3 4ZW5 4ZW6 4ZW7 4ZW8 4ZX3 4ZX4 4ZX5 More...
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