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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4074
Target Type SINGLE PROTEIN
Preferred Name Angiotensin-converting enzyme
Synonyms ACE | ACE | Angiotensin-converting enzyme | Angiotensin-converting enzyme, soluble form | CD_antigen=CD143 | DCP1 | Dipeptidyl carboxypeptidase I | Kininase II
Organism Oryctolagus cuniculus
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m2 family

Target Components

Component Description Relationship Accession
Angiotensin-converting enzyme SINGLE PROTEIN P12822

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005737 (cytoplasm)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004180 (carboxypeptidase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008241 (peptidyl-dipeptidase activity)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)

Target Cross References - Protein

canSAR P12822
UniProt O02852 P12822 P22968

Target Cross References - Domain

InterPro IPR001548 (Peptidase_M2.)
Pfam PF01401 (Peptidase_M2)
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