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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3988561
Target Type PROTEIN FAMILY
Preferred Name Human leukocyte antigen DR beta chain
Synonyms Clone P2-beta-3 | DR beta-5 | DR-1 | DR-12 | DR-13 | DR-14 | DR-16 | DR-4 | DR-5 | DR-7 | DR-8 | DR-9 | DR1 | DR12 | DR13 | DR14 | DR16 | DR2-beta-2 | DR4 | DR5 | DR7 | DR8 | DR9 | DRw10 | DRw11 | DRw8 | DW2.2/DR2.2 | Dw2 | HLA class II histocompatibility antigen, DR beta 3 chain | HLA class II histocompatibility antigen, DR beta 4 chain | HLA class II histocompatibility antigen, DR beta 5 chain | HLA class II histocompatibility antigen, DRB1-1 beta chain | HLA class II histocompatibility antigen, DRB1-10 beta chain | HLA class II histocompatibility antigen, DRB1-11 beta chain | HLA class II histocompatibility antigen, DRB1-12 beta chain | HLA class II histocompatibility antigen, DRB1-13 beta chain | HLA class II histocompatibility antigen, DRB1-14 beta chain | HLA class II histocompatibility antigen, DRB1-15 beta chain | HLA class II histocompatibility antigen, DRB1-16 beta chain | HLA class II histocompatibility antigen, DRB1-3 chain | HLA class II histocompatibility antigen, DRB1-4 beta chain | HLA class II histocompatibility antigen, DRB1-7 beta chain | HLA class II histocompatibility antigen, DRB1-8 beta chain | HLA class II histocompatibility antigen, DRB1-9 beta chain | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB1 | HLA-DRB2 | HLA-DRB3 | HLA-DRB4 | HLA-DRB5 | MHC class II antigen DRB1*1 | MHC class II antigen DRB1*10 | MHC class II antigen DRB1*11 | MHC class II antigen DRB1*12 | MHC class II antigen DRB1*13 | MHC class II antigen DRB1*14 | MHC class II antigen DRB1*15 | MHC class II antigen DRB1*16 | MHC class II antigen DRB1*3 | MHC class II antigen DRB1*4 | MHC class II antigen DRB1*7 | MHC class II antigen DRB1*8 | MHC class II antigen DRB1*9 | MHC class II antigen DRB3 | MHC class II antigen DRB4 | MHC class II antigen DRB5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein
  • surface antigen

Target Components

Component Description Relationship Accession
HLA class II histocompatibility antigen, DRB1-13 beta chain GROUP MEMBER Q5Y7A7
HLA class II histocompatibility antigen, DRB1-14 beta chain GROUP MEMBER Q9GIY3
HLA class II histocompatibility antigen, DRB1-1 beta chain GROUP MEMBER P04229
HLA class II histocompatibility antigen, DRB1-12 beta chain GROUP MEMBER Q95IE3
HLA class II histocompatibility antigen, DRB1-16 beta chain GROUP MEMBER Q29974
HLA class II histocompatibility antigen, DRB1-8 beta chain GROUP MEMBER Q30134
HLA class II histocompatibility antigen, DRB1-15 beta chain GROUP MEMBER P01911
HLA class II histocompatibility antigen, DRB1-4 beta chain GROUP MEMBER P13760
HLA class II histocompatibility antigen, DRB1-9 beta chain GROUP MEMBER Q9TQE0
HLA class II histocompatibility antigen, DRB1-7 beta chain GROUP MEMBER P13761
HLA class II histocompatibility antigen, DRB1-3 chain GROUP MEMBER P01912
HLA class II histocompatibility antigen, DRB1-11 beta chain GROUP MEMBER P20039
HLA class II histocompatibility antigen, DRB1-10 beta chain GROUP MEMBER Q30167
HLA class II histocompatibility antigen, DR beta 3 chain GROUP MEMBER P79483
HLA class II histocompatibility antigen, DR beta 5 chain GROUP MEMBER Q30154
HLA class II histocompatibility antigen, DR beta 4 chain GROUP MEMBER P13762

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3460 HLA class II histocompatibility antigen DRB3-1 SINGLE PROTEIN
CHEMBL3831291 HLA class II histocompatibility antigen, DRB1-15 beta chain SINGLE PROTEIN
CHEMBL1943 HLA class II histocompatibility antigen DRB1-1 SINGLE PROTEIN
CHEMBL3580495 HLA class II histocompatibility antigen, DRB1-10 beta chain SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL2108252 APOLIZUMAB Human leukocyte antigen DR beta chain inhibitor 2 DOI PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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