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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3784910
Target Type SINGLE PROTEIN
Preferred Name Basic phospholipase A2 VRV-PL-VIIIa
Synonyms Basic phospholipase A2 VRV-PL-VIIIa | DPLA2 | PLA24 | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 4 | svPLA2
Organism Daboia russelii
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Basic phospholipase A2 VRV-PL-VIIIa SINGLE PROTEIN P59071

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0072556 (other organism presynaptic membrane)
GO Molecular Function GO:0004623 (phospholipase A2 activity)
GO:0005509 (calcium ion binding)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO:0090729 (toxin activity)
GO:0102567 (phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine))
GO:0102568 (phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine))
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006644 (phospholipid metabolic process)
GO:0009405 (pathogenesis)
GO:0016042 (lipid catabolic process)
GO:0050482 (arachidonic acid secretion)

Target Cross References - Protein

UniProt P59071

Target Cross References - Domain

InterPro IPR001211 (PLipase_A2.)
IPR016090 (PLipase_A2_dom.)
IPR033112 (PLipase_A2_Asp_AS.)
IPR033113 (PLipase_A2_His_AS.)
IPR036444 (PLipase_A2_dom_sf.)
Pfam PF00068 (Phospholip_A2_1)

Target Cross References - Structure

PDBe 1CL5 1FB2 1FV0 1JQ8 1JQ9 1KPM 1OXL 1OYF 1SKG 1SQZ 1SV3 1SV9 1SXK 1TDV 1TG1 1TG4 1TGM 1TH6 1TJ9 1TJK 1TK4 1TP2 1Y38 1ZR8 More...
CREDO 1CL5 1FB2 1FV0 1JQ8 1JQ9 1KPM 1OXL 1OYF 1SKG 1SQZ 1SV3 1SV9 1SXK 1TDV 1TG1 1TG4 1TGM 1TH6 1TJ9 1TJK 1TK4 1TP2 1Y38 1ZR8 More...
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