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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3781
Target Type SINGLE PROTEIN
Preferred Name Serotonin 3b (5-HT3b) receptor
Synonyms 5-HT3-B | 5-HT3B | 5-hydroxytryptamine receptor 3B | Htr3b | Serotonin receptor 3B
Organism Mus musculus
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > 5ht3 receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 3B SINGLE PROTEIN Q9JHJ5

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111333 Serotonin 3 receptor (5HT3) PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0005892 (acetylcholine-gated channel complex)
GO:0009986 (cell surface)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0045211 (postsynaptic membrane)
GO:1904602 (serotonin-activated cation-selective channel complex)
GO Molecular Function GO:0004889 (acetylcholine-activated cation-selective channel activity)
GO:0004993 (G-protein coupled serotonin receptor activity)
GO:0005230 (extracellular ligand-gated ion channel activity)
GO:0005232 (serotonin-activated cation-selective channel activity)
GO:0015276 (ligand-gated ion channel activity)
GO:0015464 (acetylcholine receptor activity)
GO:0042166 (acetylcholine binding)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0007210 (serotonin receptor signaling pathway)
GO:0007271 (synaptic transmission, cholinergic)
GO:0034220 (ion transmembrane transport)
GO:0098655 (cation transmembrane transport)

Target Cross References - Protein

canSAR Q9JHJ5
IntAct Q9JHJ5
Guide to Pharmacology 374
Reactome R-MMU-975298 (Ligand-gated ion channel transport.)
UniProt Q9JHJ5

Target Cross References - Domain

InterPro IPR006029 (Neurotrans-gated_channel_TM.)
IPR006201 (Neur_channel.)
IPR006202 (Neur_chan_lig-bd.)
IPR008132 (5HT3_rcpt.)
IPR008134 (5HT3_rcpt_B.)
IPR027361 (Acetylcholine_rcpt_TM.)
Pfam PF02931 (Neur_chan_LBD)
PF02932 (Neur_chan_memb)
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