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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3554
Target Type SINGLE PROTEIN
Preferred Name 3-dehydroquinate synthase
Synonyms 3-dehydroquinate synthase | DHQS | aroB
Organism Escherichia coli K-12
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
3-dehydroquinate synthase SINGLE PROTEIN P07639

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003856 (3-dehydroquinate synthase activity)
GO:0005515 (protein binding)
GO:0008270 (zinc ion binding)
GO:0016829 (lyase activity)
GO:0016838 (carbon-oxygen lyase activity, acting on phosphates)
GO:0046872 (metal ion binding)
GO:0070403 (NAD+ binding)
GO Biological Process GO:0008652 (cellular amino acid biosynthetic process)
GO:0009073 (aromatic amino acid family biosynthetic process)
GO:0009423 (chorismate biosynthetic process)

Target Cross References - Protein

canSAR P07639
IntAct P07639
UniProt P07639 Q2M754

Target Cross References - Domain

InterPro IPR016037 (DHQ_synth_AroB.)
IPR030960 (DHQS/DOIS.)
IPR030963 (DHQ_synth_fam.)
Pfam PF01761 (DHQ_synthase)
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