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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3455
Target Type SINGLE PROTEIN
Preferred Name Anandamide amidohydrolase
Synonyms Anandamide amidohydrolase 1 | Faah | Faah1 | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Fatty-acid amide hydrolase 1 SINGLE PROTEIN O08914

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0000139 (Golgi membrane)
GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0005794 (Golgi apparatus)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031090 (organelle membrane)
GO Molecular Function GO:0004040 (amidase activity)
GO:0005543 (phospholipid binding)
GO:0008289 (lipid binding)
GO:0016787 (hydrolase activity)
GO:0016788 (hydrolase activity, acting on ester bonds)
GO:0017064 (fatty acid amide hydrolase activity)
GO:0042802 (identical protein binding)
GO:0042803 (protein homodimerization activity)
GO:0047372 (acylglycerol lipase activity)
GO:0102077 (oleamide hydrolase activity)
GO:0103073 (anandamide amidohydrolase activity)
GO Biological Process GO:0009062 (fatty acid catabolic process)

Target Cross References - Protein

canSAR O08914
Reactome R-MMU-2142753 (Arachidonic acid metabolism.)
UniProt O08914 Q922S0 Q9DBF5

Target Cross References - Domain

InterPro IPR000120 (Amidase.)
IPR020556 (Amidase_CS.)
IPR023631 (Amidase_dom.)
IPR030560 (FAAH.)
IPR036928 (AS_sf.)
Pfam PF01425 (Amidase)
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