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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3423
Target Type SINGLE PROTEIN
Preferred Name Methionine aminopeptidase
Synonyms JW0163 | MAP | MetAP | Methionine aminopeptidase | Peptidase M | map
Organism Escherichia coli K-12
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mg clan > metallo protease m24a subfamily

Target Components

Component Description Relationship Accession
Methionine aminopeptidase SINGLE PROTEIN P0AE18

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0008198 (ferrous iron binding)
GO:0008233 (peptidase activity)
GO:0008235 (metalloexopeptidase activity)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO:0070006 (metalloaminopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0070084 (protein initiator methionine removal)

Target Cross References - Protein

canSAR P0AE18
IntAct P0AE18
UniProt P07906 P0AE18

Target Cross References - Domain

InterPro IPR000994 (Pept_M24.)
IPR001714 (Pept_M24_MAP.)
IPR002467 (Pept_M24A_MAP1.)
Pfam PF00557 (Peptidase_M24)

Target Cross References - Structure

PDBe 1C21 1C22 1C23 1C24 1C27 1MAT 1XNZ 1YVM 2BB7 2EVC 2EVM 2EVO 2GG0 2GG2 2GG3 2GG5 2GG7 2GG8 2GG9 2GGB 2GGC 2GTX 2GU4 2GU5 More...
CREDO 1C21 1C22 1C23 1C24 1C27 1MAT 1XNZ 1YVM 2BB7 2EVC 2EVM 2EVO 2GG0 2GG2 2GG3 2GG5 2GG7 2GG8 2GG9 2GGB 2GGC 2GTX 2GU4 2GU5 More...
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