ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3360
Target Type SINGLE PROTEIN
Preferred Name Adenosine A3 receptor
Synonyms Adenosine receptor A3 | Adora3 | TGPCR1
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > nucleotide-like receptor (family a gpcr) > adenosine receptor

Target Components

Component Description Relationship Accession
Adenosine receptor A3 SINGLE PROTEIN P28647

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2096681 Adenosine receptors; A1 & A3 SELECTIVITY GROUP
CHEMBL2111386 Adenosine receptor PROTEIN FAMILY
CHEMBL2111403 Adenosine receptor A2a and A3 SELECTIVITY GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0042734 (presynaptic membrane)
GO Molecular Function GO:0001609 (G-protein coupled adenosine receptor activity)
GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO Biological Process GO:0001973 (adenosine receptor signaling pathway)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0014061 (regulation of norepinephrine secretion)

Target Cross References - Protein

canSAR P28647
Guide to Pharmacology 21
MICAD NBK23295 (Adenosine A3 receptors)
Reactome R-RNO-417973 (Adenosine P1 receptors.)
R-RNO-418594 (G alpha (i) signalling events.)
UniProt P28647 Q63792

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000466 (Adeno_A3_rcpt.)
IPR001634 (Adenosn_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
spacer
spacer