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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3345
Target Type SINGLE PROTEIN
Preferred Name 3-dehydroquinate dehydratase
Synonyms 3-dehydroquinase | 3-dehydroquinate dehydratase | Type II DHQase | aroD | aroQ
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
3-dehydroquinate dehydratase SINGLE PROTEIN P9WPX7

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0003855 (3-dehydroquinate dehydratase activity)
GO:0016829 (lyase activity)
GO Biological Process GO:0008652 (cellular amino acid biosynthetic process)
GO:0009073 (aromatic amino acid family biosynthetic process)
GO:0009423 (chorismate biosynthetic process)
GO:0040007 (growth)

Target Cross References - Protein

canSAR P0A4Z6
Reactome R-MTU-964903 (Chorismate via Shikimate Pathway.)
UniProt L0TCT6 P0A4Z6 P36918 P95016 P9WPX7

Target Cross References - Domain

InterPro IPR001874 (DHquinase_II.)
IPR018509 (DHquinase_II_CS.)
Pfam PF01220 (DHquinase_II)

Target Cross References - Structure

PDBe 1H05 1H0R 1H0S 2DHQ 2XB8 2Y71 2Y76 2Y77 3N59 3N76 3N7A 3N86 3N87 3N8K 3N8N 4B6O 4B6P 4B6Q 4CIV 4CIW 4CIX 4CIY 4CKW 4CKX More...
CREDO 1H05 1H0R 1H0S 2DHQ 2XB8 2Y71 2Y76 2Y77 3N59 3N76 3N7A 3N86 3N87 3N8K 3N8N 4B6O 4B6P 4B6Q 4CIV 4CIW 4CIX 4CIY 4CKW 4CKX More...
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