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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3329078
Target Type SINGLE PROTEIN
Preferred Name Inosine-5'-monophosphate dehydrogenase
Synonyms Inosine-5'-monophosphate dehydrogenase | guaB
Organism Bacillus anthracis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Inosine-5'-monophosphate dehydrogenase SINGLE PROTEIN Q81W29

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003824 (catalytic activity)
GO:0003938 (IMP dehydrogenase activity)
GO:0016491 (oxidoreductase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006164 (purine nucleotide biosynthetic process)
GO:0006177 (GMP biosynthetic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

UniProt E9QUK9 E9QUL0 Q6I531 Q6KYS5 Q81W29

Target Cross References - Domain

InterPro IPR000644 (CBS_dom.)
IPR001093 (IMP_DH_GMPRt.)
IPR005990 (IMP_DH.)
IPR013785 (Aldolase_TIM.)
IPR015875 (IMP_DH/GMP_Rdtase_CS.)
Pfam PF00478 (IMPDH)
PF00571 (CBS)

Target Cross References - Structure

PDBe 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5URR 5URS 5UUV 5UUW 5UUZ
CREDO 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5URR 5URS 5UUV 5UUW 5UUZ
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