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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3314
Target Type SINGLE PROTEIN
Preferred Name Alpha-chymotrypsin
Synonyms Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease pa clan > serine protease s1a subfamily

Target Components

Component Description Relationship Accession
Chymotrypsinogen A SINGLE PROTEIN P00766

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005615 (extracellular space)
GO:0097180 (serine protease inhibitor complex)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO:0005515 (protein binding)
GO:0008233 (peptidase activity)
GO:0008236 (serine-type peptidase activity)
GO:0016787 (hydrolase activity)
GO:0097655 (serpin family protein binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0007586 (digestion)

Target Cross References - Protein

canSAR P00766
IntAct P00766
UniProt P00766

Target Cross References - Domain

InterPro IPR001254 (Trypsin_dom.)
IPR001314 (Peptidase_S1A.)
IPR009003 (Peptidase_S1_PA.)
IPR018114 (TRYPSIN_HIS.)
IPR033116 (TRYPSIN_SER.)
Pfam PF00089 (Trypsin)

Target Cross References - Structure

PDBe 1AB9 1ACB 1AFQ 1CA0 1CBW 1CGI 1CGJ 1CHG 1CHO 1DLK 1EX3 1GCD 1GCT 1GG6 1GGD 1GHA 1GHB 1GL0 1GL1 1GMC 1GMD 1GMH 1HJA 1K2I More...
CREDO 1AB9 1ACB 1AFQ 1CA0 1CBW 1CGI 1CGJ 1CHG 1CHO 1DLK 1EX3 1GCD 1GCT 1GG6 1GGD 1GHA 1GHB 1GL0 1GL1 1GMC 1GMD 1GMH 1HJA 1K2I More...
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