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Target Report Card

Target Name and Classification

Target ID CHEMBL3309099
Preferred Name Free fatty acid receptor 4
Synonyms Ffar4 | Free fatty acid receptor 4 | G-protein coupled receptor 120 | Gpr120 | O3far1 | Omega-3 fatty acid receptor 1
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > lipid-like ligand receptor (family a gpcr) > free fatty acid receptor

Target Components

Component Description Relationship Accession
Free fatty acid receptor 4 SINGLE PROTEIN Q2AC31

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030139 (endocytic vesicle)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0005504 (fatty acid binding)
GO:0008289 (lipid binding)
GO:0008527 (taste receptor activity)
GO:0042277 (peptide binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0010827 (regulation of glucose transport)
GO:0032870 (cellular response to hormone stimulus)
GO:0043066 (negative regulation of apoptotic process)
GO:0045444 (fat cell differentiation)
GO:0046879 (hormone secretion)
GO:0050710 (negative regulation of cytokine secretion)
GO:0050728 (negative regulation of inflammatory response)
GO:0070374 (positive regulation of ERK1 and ERK2 cascade)
GO:1901652 (response to peptide)

Target Cross References - Protein

Guide to Pharmacology 127
Reactome R-RNO-381771 (Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).)
R-RNO-416476 (G alpha (q) signalling events.)
UniProt Q2AC31

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)