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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3285
Target Type SINGLE PROTEIN
Preferred Name Alcohol dehydrogenase gamma chain
Synonyms ADH1C | ADH3 | Alcohol dehydrogenase 1C | Alcohol dehydrogenase subunit gamma
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Alcohol dehydrogenase 1C SINGLE PROTEIN P00326

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2096668 Alcohol dehydrogenase PROTEIN FAMILY
CHEMBL2363044 Alcohol dehydrogenase class I PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000248144
Ensembl ENSG00000248144
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004022 (alcohol dehydrogenase (NAD) activity)
GO:0004024 (alcohol dehydrogenase activity, zinc-dependent)
GO:0004745 (retinol dehydrogenase activity)
GO:0008270 (zinc ion binding)
GO:0016491 (oxidoreductase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006069 (ethanol oxidation)
GO:0055114 (oxidation-reduction process)
Wikipedia ADH1C

Target Cross References - Protein

canSAR P00326
Human Protein Atlas ENSG00000248144
Open Targets ENSG00000248144
PharmGKB PA24572
Reactome R-HSA-5365859 (RA biosynthesis pathway.)
R-HSA-71384 (Ethanol oxidation.)
UniProt P00326 Q4PJ18 Q5WRV0 Q6LBW4 Q6NWV0 Q6NZA7

Target Cross References - Domain

InterPro IPR002328 (ADH_Zn_CS.)
IPR011032 (GroES-like.)
IPR013149 (ADH_C.)
IPR013154 (ADH_N.)
IPR016040 (NAD(P)-bd_dom.)
IPR020843 (PKS_ER.)
Pfam PF00107 (ADH_zinc_N)
PF08240 (ADH_N)

Target Cross References - Structure

PDBe 1HT0 1U3W
CREDO 1HT0 1U3W
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