ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3244
Target Type SINGLE PROTEIN
Preferred Name Sulfonylurea receptor 2
Synonyms ATP-binding cassette sub-family C member 9 | Abcc9 | Sulfonylurea receptor 2 | Sur2
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • transporter > primary active transporter > atp-binding cassette > abcc subfamily

Target Components

Component Description Relationship Accession
ATP-binding cassette sub-family C member 9 SINGLE PROTEIN Q63563

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005739 (mitochondrion)
GO:0005886 (plasma membrane)
GO:0008282 (ATP-sensitive potassium channel complex)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030315 (T-tubule)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0005267 (potassium channel activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0008144 (drug binding)
GO:0008281 (sulfonylurea receptor activity)
GO:0015459 (potassium channel regulator activity)
GO:0016887 (ATPase activity)
GO:0019905 (syntaxin binding)
GO:0042626 (ATPase activity, coupled to transmembrane movement of substances)
GO:0042802 (identical protein binding)
GO Biological Process GO:0006810 (transport)
GO:0006813 (potassium ion transport)
GO:0006932 (substrate-dependent cell migration, cell contraction)
GO:0007165 (signal transduction)
GO:0010107 (potassium ion import)
GO:0042493 (response to drug)
GO:0055085 (transmembrane transport)

Target Cross References - Protein

canSAR Q63563
IntAct Q63563
UniProt O89115 Q63563

Target Cross References - Domain

InterPro IPR000388 (Sulphorea_rcpt.)
IPR001475 (ABCC9.)
IPR003439 (ABC_transporter-like.)
IPR003593 (AAA+_ATPase.)
IPR011527 (ABC1_TM_dom.)
IPR017871 (ABC_transporter_CS.)
IPR027417 (P-loop_NTPase.)
Pfam PF00005 (ABC_tran)
PF00664 (ABC_membrane)
spacer
spacer