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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3241
Target Type SINGLE PROTEIN
Preferred Name Histamine N-methyltransferase
Synonyms HMT | Histamine N-methyltransferase | Hnmt
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Histamine N-methyltransferase SINGLE PROTEIN Q01984

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0043005 (neuron projection)
GO Molecular Function GO:0008168 (methyltransferase activity)
GO:0008170 (N-methyltransferase activity)
GO:0016740 (transferase activity)
GO:0046539 (histamine N-methyltransferase activity)
GO:0098603 (selenol Se-methyltransferase activity)
GO Biological Process GO:0001695 (histamine catabolic process)
GO:0002347 (response to tumor cell)
GO:0006972 (hyperosmotic response)
GO:0007420 (brain development)
GO:0014075 (response to amine)
GO:0032259 (methylation)
GO:0035902 (response to immobilization stress)
GO:0042220 (response to cocaine)
GO:0051384 (response to glucocorticoid)
GO:0070555 (response to interleukin-1)

Target Cross References - Protein

canSAR Q01984
Reactome R-RNO-70921 (Histidine catabolism.)
UniProt Q01984 Q59JM9

Target Cross References - Domain

InterPro IPR016673 (HHMT-like.)
IPR029063 (SAM-dependent_MTases.)
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