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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3224
Target Type SINGLE PROTEIN
Preferred Name C-8 sterol isomerase
Synonyms C-8 sterol isomerase | Delta-8--delta-7 sterol isomerase | ERG2
Organism Saccharomyces cerevisiae S288c
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
C-8 sterol isomerase SINGLE PROTEIN P32352

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0000247 (C-8 sterol isomerase activity)
GO:0016853 (isomerase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006694 (steroid biosynthetic process)
GO:0006696 (ergosterol biosynthetic process)
GO:0008202 (steroid metabolic process)
GO:0016126 (sterol biosynthetic process)

Target Cross References - Protein

canSAR P32352
IntAct P32352
UniProt D6W027 P32352

Target Cross References - Domain

InterPro IPR006716 (ERG2_sigma1_rcpt-like.)
Pfam PF04622 (ERG2_Sigma1R)
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