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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3122
Target Type SINGLE PROTEIN
Preferred Name Alpha-1b adrenergic receptor
Synonyms ADRA1B | Alpha-1B adrenergic receptor | Alpha-1B adrenoceptor | Alpha-1B adrenoreceptor
Organism Mesocricetus auratus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > adrenergic receptor

Target Components

Component Description Relationship Accession
Alpha-1B adrenergic receptor SINGLE PROTEIN P18841

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005634 (nucleus)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031965 (nuclear membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004935 (adrenergic receptor activity)
GO:0004937 (alpha1-adrenergic receptor activity)
GO:0005515 (protein binding)
GO:0046982 (protein heterodimerization activity)
GO Biological Process GO:0006937 (regulation of muscle contraction)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0019229 (regulation of vasoconstriction)
GO:0043410 (positive regulation of MAPK cascade)
GO:0055117 (regulation of cardiac muscle contraction)
GO:0071875 (adrenergic receptor signaling pathway)

Target Cross References - Protein

canSAR P18841
IntAct P18841
UniProt P18841

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001115 (ADRA1B_rcpt.)
IPR002233 (ADR_fam.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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