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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3097
Target Type SINGLE PROTEIN
Preferred Name Acetylcholine receptor protein alpha chain
Synonyms Acetylcholine receptor subunit alpha | CHRNA1
Organism Torpedo californica
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > nicotinic acetylcholine receptor > nicotinic acetylcholine receptor alpha subunit

Target Components

Component Description Relationship Accession
Acetylcholine receptor subunit alpha SINGLE PROTEIN P02710

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2096975 Acetylcholine receptor PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030054 (cell junction)
GO:0045202 (synapse)
GO:0045211 (postsynaptic membrane)
GO Molecular Function GO:0004889 (acetylcholine-activated cation-selective channel activity)
GO:0005216 (ion channel activity)
GO:0005230 (extracellular ligand-gated ion channel activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0034220 (ion transmembrane transport)
GO:0098655 (cation transmembrane transport)

Target Cross References - Protein

canSAR P02710
IntAct P02710
UniProt P02710

Target Cross References - Domain

InterPro IPR002394 (Nicotinic_acetylcholine_rcpt.)
IPR006029 (Neurotrans-gated_channel_TM.)
IPR006201 (Neur_channel.)
IPR006202 (Neur_chan_lig-bd.)
IPR018000 (Neurotransmitter_ion_chnl_CS.)
IPR027361 (Acetylcholine_rcpt_TM.)
Pfam PF02931 (Neur_chan_LBD)
PF02932 (Neur_chan_memb)
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