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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3081
Target Type SINGLE PROTEIN
Preferred Name Aldose reductase
Synonyms 20-alpha-HSD | 20-alpha-hydroxysteroid dehydrogenase | AKR1B1 | AR | Aldehyde reductase | Aldose reductase
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Aldose reductase SINGLE PROTEIN P16116

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004032 (alditol:NADP+ 1-oxidoreductase activity)
GO:0016491 (oxidoreductase activity)
GO:0047006 (17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity)
GO Biological Process GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P16116
UniProt P16116

Target Cross References - Domain

InterPro IPR018170 (Aldo/ket_reductase_CS.)
IPR020471 (Aldo/keto_reductase.)
IPR023210 (NADP_OxRdtase_dom.)
Pfam PF00248 (Aldo_ket_red)
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