ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3046
Target Type SINGLE PROTEIN
Preferred Name Sialidase 3
Synonyms Ganglioside sialidase | Membrane sialidase | N-acetyl-alpha-neuraminidase 3 | NEU3 | Sialidase-3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Sialidase-3 SINGLE PROTEIN Q9UQ49

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000162139
Ensembl ENSG00000162139
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0004308 (exo-alpha-sialidase activity)
GO:0016787 (hydrolase activity)
GO:0016798 (hydrolase activity, acting on glycosyl bonds)
GO:0016997 (alpha-sialidase activity)
GO:0052794 (exo-alpha-(2->3)-sialidase activity)
GO:0052795 (exo-alpha-(2->6)-sialidase activity)
GO:0052796 (exo-alpha-(2->8)-sialidase activity)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0006629 (lipid metabolic process)
GO:0006687 (glycosphingolipid metabolic process)
GO:0006689 (ganglioside catabolic process)
GO:0008152 (metabolic process)
GO:0009313 (oligosaccharide catabolic process)
GO:0016042 (lipid catabolic process)
Wikipedia NEU3

Target Cross References - Protein

canSAR Q9UQ49
Human Protein Atlas ENSG00000162139
Open Targets ENSG00000162139
Reactome R-HSA-1660662 (Glycosphingolipid metabolism.)
R-HSA-4085001 (Sialic acid metabolism.)
UniProt A8K327 Q9NQE1 Q9UQ49

Target Cross References - Domain

InterPro IPR011040 (Sialidases.)
IPR026856 (Sialidase_fam.)
IPR026944 (Sialidase-3.)
Pfam PF13088 (BNR_2)
spacer
spacer