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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3011
Preferred Name Acetylcholine receptor protein delta chain
Synonyms ACHRD | Acetylcholine receptor subunit delta | CHRND
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > nicotinic acetylcholine receptor > nicotinic acetylcholine receptor delta subunit

Target Components

Component Description Relationship Accession
Acetylcholine receptor subunit delta SINGLE PROTEIN Q07001

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL1907588 Acetylcholine receptor; alpha1/beta1/delta/gamma PROTEIN COMPLEX
CHEMBL2362997 Muscle-type nicotinic acetylcholine receptor PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000135902
Ensembl ENSG00000135902
GO Cellular Component GO:0005654 (nucleoplasm)
GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO:0005892 (acetylcholine-gated channel complex)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030054 (cell junction)
GO:0045202 (synapse)
GO:0045211 (postsynaptic membrane)
GO Molecular Function GO:0004888 (transmembrane signaling receptor activity)
GO:0005216 (ion channel activity)
GO:0005230 (extracellular ligand-gated ion channel activity)
GO:0015276 (ligand-gated ion channel activity)
GO:0022848 (acetylcholine-gated cation channel activity)
GO:0042166 (acetylcholine binding)
GO Biological Process GO:0003009 (skeletal muscle contraction)
GO:0006811 (ion transport)
GO:0006812 (cation transport)
GO:0006936 (muscle contraction)
GO:0007165 (signal transduction)
GO:0007271 (synaptic transmission, cholinergic)
GO:0007274 (neuromuscular synaptic transmission)
GO:0034220 (ion transmembrane transport)
GO:0035094 (response to nicotine)
GO:0042391 (regulation of membrane potential)
GO:0048630 (skeletal muscle tissue growth)
GO:0050881 (musculoskeletal movement)
GO:0050905 (neuromuscular process)
GO:0060078 (regulation of postsynaptic membrane potential)
GO:0060079 (excitatory postsynaptic potential)
GO:0098655 (cation transmembrane transport)
Wikipedia CHRND

Target Cross References - Protein

canSAR Q07001
CGD Myasthenic syndrome, congenital, fast channel; Myasthenic syndrome, slow-channel congenital
Human Protein Atlas ENSG00000135902
IntAct Q07001
Guide to Pharmacology 476
Open Targets ENSG00000135902
PharmGKB PA26497
Pharos Q07001 (Tclin)
Reactome R-HSA-629587 (Highly sodium permeable acetylcholine nicotinic receptors.)
UniProt A8K661 B4DT92 Q07001 Q52LH4

Target Cross References - Domain

InterPro IPR002394 (Nicotinic_acetylcholine_rcpt.)
IPR006029 (Neurotrans-gated_channel_TM.)
IPR006201 (Neur_channel.)
IPR006202 (Neur_chan_lig-bd.)
IPR018000 (Neurotransmitter_ion_chnl_CS.)
IPR036719 (Neuro-gated_channel_TM_sf.)
IPR036734 (Neur_chan_lig-bd_sf.)
Pfam PF02931 (Neur_chan_LBD)
PF02932 (Neur_chan_memb)