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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2927
Target Type SINGLE PROTEIN
Preferred Name Cytochrome P450 11B1
Synonyms CYP11B1 | CYPXIB1 | Cytochrome P450 11B1, mitochondrial | Cytochrome P450C11 | Steroid 11-beta-hydroxylase
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme > cytochrome p450 > cytochrome p450 family 11 > cytochrome p450 family 11b > cytochrome p450 11b1

Target Components

Component Description Relationship Accession
Cytochrome P450 11B1, mitochondrial SINGLE PROTEIN P15150

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005739 (mitochondrion)
GO:0016020 (membrane)
GO:0031966 (mitochondrial membrane)
GO Molecular Function GO:0004497 (monooxygenase activity)
GO:0004507 (steroid 11-beta-monooxygenase activity)
GO:0005506 (iron ion binding)
GO:0016491 (oxidoreductase activity)
GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
GO:0020037 (heme binding)
GO:0046872 (metal ion binding)
GO:0047783 (corticosterone 18-monooxygenase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006694 (steroid biosynthetic process)
GO:0008202 (steroid metabolic process)
GO:0032342 (aldosterone biosynthetic process)
GO:0034650 (cortisol metabolic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P15150
UniProt P15150 Q29457

Target Cross References - Domain

InterPro IPR001128 (Cyt_P450.)
IPR002401 (Cyt_P450_E_grp-I.)
IPR017972 (Cyt_P450_CS.)
IPR036396 (Cyt_P450_sf.)
Pfam PF00067 (p450)
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