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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2723
Target Type SINGLE PROTEIN
Preferred Name Dual specificity phosphatase Cdc25B
Synonyms Cdc25b | Cdc25m2 | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme > phosphatase > protein phosphatase > serine/threonine/tyrosine protein phosphatase

Target Components

Component Description Relationship Accession
M-phase inducer phosphatase 2 SINGLE PROTEIN P30306

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0000922 (spindle pole)
GO:0005622 (intracellular)
GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005813 (centrosome)
GO:0005815 (microtubule organizing center)
GO:0005856 (cytoskeleton)
GO Molecular Function GO:0004721 (phosphoprotein phosphatase activity)
GO:0004725 (protein tyrosine phosphatase activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0019901 (protein kinase binding)
GO Biological Process GO:0000278 (mitotic cell cycle)
GO:0001556 (oocyte maturation)
GO:0006468 (protein phosphorylation)
GO:0006470 (protein dephosphorylation)
GO:0007049 (cell cycle)
GO:0007144 (female meiosis I)
GO:0032467 (positive regulation of cytokinesis)
GO:0035335 (peptidyl-tyrosine dephosphorylation)
GO:0045860 (positive regulation of protein kinase activity)
GO:0045931 (positive regulation of mitotic cell cycle)
GO:0051301 (cell division)
GO:1902751 (positive regulation of cell cycle G2/M phase transition)

Target Cross References - Protein

canSAR P30306
IntAct P30306
Reactome R-MMU-69273 (Cyclin A/B1/B2 associated events during G2/M transition.)
R-MMU-69656 (Cyclin A:Cdk2-associated events at S phase entry.)
UniProt P30306 Q99LP3

Target Cross References - Domain

InterPro IPR000751 (MPI_Phosphatase.)
IPR001763 (Rhodanese-like_dom.)
IPR036873 (Rhodanese-like_dom_sf.)
Pfam PF00581 (Rhodanese)
PF06617 (M-inducer_phosp)
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