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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2699
Target Type SINGLE PROTEIN
Preferred Name Pancreatic alpha-amylase
Synonyms 1,4-alpha-D-glucan glucanohydrolase | Amy2 | PA | Pancreatic alpha-amylase
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Pancreatic alpha-amylase SINGLE PROTEIN P00689

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005615 (extracellular space)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0004556 (alpha-amylase activity)
GO:0005509 (calcium ion binding)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0016798 (hydrolase activity, acting on glycosyl bonds)
GO:0031404 (chloride ion binding)
GO:0043169 (cation binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0008152 (metabolic process)
GO:0016052 (carbohydrate catabolic process)

Target Cross References - Protein

canSAR P00689
IntAct P00689
UniProt P00689

Target Cross References - Domain

InterPro IPR006046 (Alpha_amylase.)
IPR006047 (Glyco_hydro_13_cat_dom.)
IPR006048 (A-amylase/branching_C.)
IPR013780 (Glyco_hydro_b.)
IPR013781 (Glyco_hydro_catalytic_dom.)
IPR017853 (Glycoside_hydrolase_SF.)
IPR031319 (A-amylase_C.)
Pfam PF00128 (Alpha-amylase)
PF02806 (Alpha-amylase_C)
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