ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2619
Target Type SINGLE PROTEIN
Preferred Name Serotonin 5b (5-HT5b) receptor
Synonyms 5-HT-5B | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5ht5b | Htr5b | MR22 | Serotonin receptor 5B
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > serotonin receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 5B SINGLE PROTEIN P35365

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2094123 Serotonin (5-HT) receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004993 (G-protein coupled serotonin receptor activity)
GO:0008144 (drug binding)
GO:0051378 (serotonin binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007210 (serotonin receptor signaling pathway)

Target Cross References - Protein

canSAR P35365
UniProt P35365

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000431 (5HT5B_rcpt.)
IPR002231 (5HT_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
spacer
spacer