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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2526
Target Type SINGLE PROTEIN
Preferred Name Methionine aminopeptidase 1
Synonyms MAP 1 | MAP1 | MetAP 1 | Methionine aminopeptidase 1 | Peptidase M 1
Organism Saccharomyces cerevisiae S288c
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mg clan > metallo protease m24a subfamily

Target Components

Component Description Relationship Accession
Methionine aminopeptidase 1 SINGLE PROTEIN Q01662

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0022626 (cytosolic ribosome)
GO Molecular Function GO:0003729 (mRNA binding)
GO:0004177 (aminopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008235 (metalloexopeptidase activity)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO:0070006 (metalloaminopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0010629 (negative regulation of gene expression)
GO:0035551 (protein initiator methionine removal involved in protein maturation)
GO:0070084 (protein initiator methionine removal)

Target Cross References - Protein

canSAR Q01662
IntAct Q01662
Reactome R-SCE-2514859 (Inactivation, recovery and regulation of the phototransduction cascade.)
UniProt D6VYP2 Q01662

Target Cross References - Domain

InterPro IPR000994 (Pept_M24.)
IPR001714 (Pept_M24_MAP.)
IPR002467 (Pept_M24A_MAP1.)
IPR031615 (Zfn-C6H2.)
Pfam PF00557 (Peptidase_M24)
PF15801 (zf-C6H2)
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