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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2426
Target Type SINGLE PROTEIN
Preferred Name Casein kinase I gamma 1
Synonyms CKI-gamma 1 | CSNK1G1 | Casein kinase I isoform gamma-1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > ck1 protein kinase group > ck1 protein kinase ck1 family

Target Components

Component Description Relationship Accession
Casein kinase I isoform gamma-1 SINGLE PROTEIN Q9HCP0

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111458 Casein kinase I PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000169118
Ensembl ENSG00000169118
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0006897 (endocytosis)
GO:0008360 (regulation of cell shape)
GO:0016055 (Wnt signaling pathway)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)

Target Cross References - Protein

canSAR Q9HCP0
Human Protein Atlas ENSG00000169118
IntAct Q9HCP0
Guide to Pharmacology 1999
Open Targets ENSG00000169118
PharmGKB PA26954
Pharos Q9HCP0 (Tbio)
UniProt Q5JPH1 Q96AE9 Q9HCP0 Q9HCP1

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR022247 (Casein_kinase-1_gamma_C.)
Pfam PF00069 (Pkinase)
PF12605 (CK1gamma_C)

Target Cross References - Structure

PDBe 2CMW
CREDO 2CMW
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