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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2364167
Target Type PROTEIN COMPLEX
Preferred Name Interleukin-2 receptor
Synonyms CD_antigen=CD122 | CD_antigen=CD132 | CD_antigen=CD25 | Cytokine receptor common subunit gamma | High affinity IL-2 receptor subunit beta | IL-2 receptor subunit alpha | IL-2 receptor subunit beta | IL-2 receptor subunit gamma | IL-2-RA | IL-2R subunit alpha | IL-2R subunit beta | IL-2R subunit gamma | IL-2RB | IL-2RG | IL2-RA | IL2RA | IL2RB | IL2RG | Interleukin-2 receptor subunit alpha | Interleukin-2 receptor subunit beta | Interleukin-2 receptor subunit gamma | TAC antigen | gammaC | p55 | p64 | p70-75 | p75
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor

Target Components

Component Description Relationship Accession
Interleukin-2 receptor subunit alpha PROTEIN SUBUNIT P01589
Interleukin-2 receptor subunit beta PROTEIN SUBUNIT P14784
Cytokine receptor common subunit gamma PROTEIN SUBUNIT P31785

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3276 Interleukin-2 receptor beta chain SINGLE PROTEIN
CHEMBL1778 Interleukin-2 receptor alpha chain SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL1201550 DENILEUKIN DIFTITOX Interleukin-2 receptor binding agent 4 DailyMed FDA PubMed
CHEMBL1201439 BASILIXIMAB Interleukin-2 receptor inhibitor 4 DailyMed
CHEMBL1201438 HUMAN INTERLEUKIN-2 Interleukin-2 receptor agonist 4 DailyMed
CHEMBL1201605 DACLIZUMAB Interleukin-2 receptor inhibitor 4 DailyMed FDA

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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