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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2364153
Target Type PROTEIN COMPLEX
Preferred Name Interleukin-12
Synonyms CLMF p35 | CLMF p40 | Cytotoxic lymphocyte maturation factor 35 kDa subunit | Cytotoxic lymphocyte maturation factor 40 kDa subunit | IL-12 subunit p35 | IL-12 subunit p40 | IL-12A | IL-12B | IL12A | IL12B | Interleukin-12 subunit alpha | Interleukin-12 subunit beta | NK cell stimulatory factor chain 1 | NK cell stimulatory factor chain 2 | NKSF1 | NKSF1 | NKSF2 | NKSF2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • secreted protein

Target Components

Component Description Relationship Accession
Interleukin-12 subunit beta PROTEIN SUBUNIT P29460
Interleukin-12 subunit alpha PROTEIN SUBUNIT P29459

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2364154 Interleukin-23 PROTEIN COMPLEX
CHEMBL3580484 Interleukin-12 subunit beta SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL1201835 USTEKINUMAB Interleukin-12 inhibitor 4 DailyMed
CHEMBL1742995 BRIAKINUMAB Interleukin-12 inhibitor 3 PubMed PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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