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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2331
Target Type SINGLE PROTEIN
Preferred Name Phenylethanolamine N-methyltransferase
Synonyms Noradrenaline N-methyltransferase | PNMT | PNMTase | Phenylethanolamine N-methyltransferase
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Phenylethanolamine N-methyltransferase SINGLE PROTEIN P10938

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0004603 (phenylethanolamine N-methyltransferase activity)
GO:0008168 (methyltransferase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0032259 (methylation)
GO:0042418 (epinephrine biosynthetic process)
GO:0042423 (catecholamine biosynthetic process)

Target Cross References - Protein

canSAR P10938
UniProt P10938

Target Cross References - Domain

InterPro IPR000940 (NNMT_TEMT_trans.)
IPR025820 (NNMT/PNMT/TEMT_CS.)
IPR029063 (SAM-dependent_MTases.)
Pfam PF01234 (NNMT_PNMT_TEMT)
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