ChEMBL logo


ChEMBL Statistics
  Loading Statistics...

Target Report Card

Target Name and Classification

Target ID CHEMBL2216739
Preferred Name Carnitine O-palmitoyltransferase 1, muscle isoform
Synonyms CPT I | CPT1-M | CPT1B | CPTI-M | Carnitine O-palmitoyltransferase 1, muscle isoform | Carnitine O-palmitoyltransferase I, muscle isoform | Carnitine palmitoyltransferase 1B | Carnitine palmitoyltransferase I-like protein | KIAA1670
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > group translocator

Target Components

Component Description Relationship Accession
Carnitine O-palmitoyltransferase 1, muscle isoform SINGLE PROTEIN Q92523

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000205560
Ensembl ENSG00000205560
GO Cellular Component GO:0005739 (mitochondrion)
GO:0005741 (mitochondrial outer membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0004095 (carnitine O-palmitoyltransferase activity)
GO:0005515 (protein binding)
GO:0016740 (transferase activity)
GO:0016746 (transferase activity, transferring acyl groups)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006631 (fatty acid metabolic process)
GO:0006635 (fatty acid beta-oxidation)
GO:0006810 (transport)
GO:0006853 (carnitine shuttle)
GO:0015909 (long-chain fatty acid transport)

Target Cross References - Protein

Human Protein Atlas ENSG00000205560
IntAct Q92523
Open Targets ENSG00000205560
PharmGKB PA26848
Reactome R-HSA-200425 (Import of palmitoyl-CoA into the mitochondrial matrix.)
R-HSA-5362517 (Signaling by Retinoic Acid.)
UniProt B7Z4U4 B7Z5T8 E9PCP2 Q13389 Q92523 Q99655 Q9BY90

Target Cross References - Domain

InterPro IPR000542 (Carn_acyl_trans.)
IPR032476 (CPT_N.)
Pfam PF00755 (Carn_acyltransf)
PF16484 (CPT_N)