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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2073679
Target Type SINGLE PROTEIN
Preferred Name Solute carrier organic anion transporter family member 4A1
Synonyms Colon organic anion transporter | OATP-E | OATP-RP1 | OATP1 | OATP4A1 | OATP4A1 | OATPE | OATPRP1 | Organic anion transporter polypeptide-related protein 1 | Organic anion-transporting polypeptide E | POAT | SLC21A12 | SLCO4A1 | Sodium-independent organic anion transporter E | Solute carrier family 21 member 12 | Solute carrier organic anion transporter family member 4A1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc21/slco family of organic anion transporting polypeptides

Target Components

Component Description Relationship Accession
Solute carrier organic anion transporter family member 4A1 SINGLE PROTEIN Q96BD0

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000101187
Ensembl ENSG00000101187
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0005215 (transporter activity)
GO:0015347 (sodium-independent organic anion transmembrane transporter activity)
GO:0015349 (thyroid hormone transmembrane transporter activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0042403 (thyroid hormone metabolic process)
GO:0043252 (sodium-independent organic anion transport)
GO:0070327 (thyroid hormone transport)

Target Cross References - Protein

Human Protein Atlas ENSG00000101187
IntAct Q96BD0
Open Targets ENSG00000101187
PharmGKB PA35838
Reactome R-HSA-879518 (Transport of organic anions.)
UniProt Q96BD0 Q9H4T7 Q9H4T8 Q9H8P2 Q9NWX8 Q9UI35 Q9UIG7

Target Cross References - Domain

InterPro IPR002350 (Kazal_dom.)
IPR004156 (OA_transporter.)
IPR020846 (MFS_dom.)
Pfam PF03137 (OATP)
PF07648 (Kazal_2)
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