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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2065
Target Type SINGLE PROTEIN
Preferred Name Beta-lactamase TEM
Synonyms Beta-lactamase TEM | IRT-4 | Penicillinase | TEM-1 | TEM-16/CAZ-7 | TEM-2 | TEM-24/CAZ-6 | TEM-3 | TEM-4 | TEM-5 | TEM-6 | TEM-8/CAZ-2 | bla | blaT-3 | blaT-4 | blaT-5 | blaT-6
Organism Escherichia coli
Species Group No
Protein Target Classification
  • enzyme > hydrolase

Target Components

Component Description Relationship Accession
Beta-lactamase TEM SINGLE PROTEIN P62593

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2364670 Bacterial beta-lactamase TEM SINGLE PROTEIN

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0005515 (protein binding)
GO:0008800 (beta-lactamase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0030655 (beta-lactam antibiotic catabolic process)
GO:0046677 (response to antibiotic)

Target Cross References - Protein

IntAct P62593
UniProt P00810 P62593 Q47313

Target Cross References - Domain

InterPro IPR000871 (Beta-lactam_class-A.)
IPR012338 (Beta-lactam/transpept-like.)
IPR023650 (Beta-lactam_class-A_AS.)

Target Cross References - Structure

PDBe 1AXB 1BT5 1BTL 1CK3 1ERM 1ERO 1ERQ 1ESU 1FQG 1JTD 1JTG 1JVJ 1JWP 1JWV 1JWZ 1LHY 1LI0 1LI9 1M40 1NXY 1NY0 1NYM 1NYY 1PZO More...
CREDO 1AXB 1BT5 1BTL 1CK3 1ERM 1ERO 1ERQ 1ESU 1FQG 1JTD 1JTG 1JVJ 1JWP 1JWV 1JWZ 1LHY 1LI0 1LI9 1M40 1NXY 1NY0 1NYM 1NYY 1PZO More...
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